منابع مشابه
Ocular drug delivery nanowafer with enhanced therapeutic efficacy.
Presently, eye injuries are treated by topical eye drop therapy. Because of the ocular surface barriers, topical eye drops must be applied several times in a day, causing side effects such as glaucoma, cataract, and poor patient compliance. This article presents the development of a nanowafer drug delivery system in which the polymer and the drug work synergistically to elicit an enhanced thera...
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Efficacy of therapeutic drug monitoring (TDM) of vancomycin (VCM) was retrospectively investigated in 184 patients with methicillin-resistant Staphylococcus aureus (MRSA) infection. The incidence of nephrotoxicity was compared between the patients who received TDM practice (TDM group, n=73) and did not (non-TDM group, n=111). Creatinine clearance (CLcr) values decreased significantly after the ...
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Over the last few decades, nanocarriers for drug delivery have emerged as powerful tools with unquestionable potential to improve the therapeutic efficacy of anticancer drugs. Many colloidal drug delivery systems are underdevelopment to ameliorate the site specificity of drug action and reduce the systemic side effects. By virtue of their small size they can be injected intravenously and dispos...
متن کاملEffectiveness of emotion regulation training on increasing self-efficacy and well-being in drug-dependent individuals
Background: Emotion plays an important role in adapting to life changes and stressful events. Difficulty regulating emotions is one of the problems drug abusers often face. The present study aimed to determine the effectiveness of emotion regulation training on increasing self-efficacy and well-being in drug-dependent individuals. Materials and Methods: The present study had a quasi-experime...
متن کاملDossier: Drug delivery and drug efficacy Principles of transmucosal delivery of therapeutic agents
Recent advances in medicine have led to new treatment options for patients and physicians as a more developed understanding of the molecular basis of disease states is translated into new therapeutic agents. Many of these new agents are compounds that are not able to reach the bloodstream when administered by the oral route preventing the ability to enjoy the benefits this delivery route provid...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2008
ISSN: 0306-5251,1365-2125
DOI: 10.1111/j.1365-2125.2008.03208.x